Talc pleurodesis for pneumothorax

Background: We herein report the usefulness of two types of talc pleurodesis for secondary pneumothorax of elderly patients with persistent air leak who have severe pulmonary emphysema. Methods: We assessed 17 elderly patients with persistent air leak who received talc pleurodesis for secondary pneumothorax from April 2013 to March 2017 Talc pleurodesis is 90-95% effective at prevention of recurrent primary spontaneous pneumothorax. However, there have been reports of ARDS occurring after talc pleurodesis, mostly in patients with malignant pleural effusions, raising concerns over its use.. Bridevaux et al report results of talc pleurodesis on 418 patients with primary spontaneous pneumothorax (PSP) at nine centers in Europe.

At the present time, talc is one of the agents most commonly used for chemical pleurodesis in patients with either a spontaneous pneumothorax or a recurrent pleural effusion, even though the occasional reports of severe side effects.32, 56 There are at least 32 cases of adult respiratory failure syndrome (ARDS) following intrapleural talc. In this issue of Chest (see page 1162), Milanez and colleagues describe their experience with thoracoscopic management of spontaneous pneumothorax. They report that after the intrapleural insulflation of 2 g of sterile asbestos-free talc, only 1 of 18 patients had a recurrence over a period of follow-up ranging from 1 to over 3 years. This is an important observation because the problems. Talc pleurodesis is a specific form of chemical pleurodesis. Talc is the most effective sclerosant available for pleurodesis in malignant pleural effusion [ 1 ]. As compared to indwelling pleural catheter placement, talc pleurodesis has been shown to be equally effective in relieving dyspnea [ 2 ]. This topic will review the indications. Pneumothorax, pneumonia, emphysema, prolonged air leakage, pulmonary embolism, arrythmia, re-expansion pulmonary edema, and empyema are important complications of thoracoscopic talc insufflation. Talc pleurodesis is an effective treatment for malignant pleural effusions (MPEs). This study was designed to estimate complication rates of.

Pleurodesis is a procedure performed to obliterate the pleural space to prevent recurrent pleural effusions, pneumothorax, or to treat a persistent pneumothorax. Pleurodesis is commonly accomplished by draining the pleural fluid or intrapleural air followed by either a mechanical procedure or instilling a chemical irritant into the pleural space, which causes intense inflammation and fibrosis. The statement recommends doxycycline or talc as the preferred agent in cases where chemical pleurodesis is conducted.13 For SSP, this statement suggests intervention to prevent pneumothorax recurrence at first occurrence (in contrast to PSP), with the surgical approach as first choice and chemical pleurodesis as an option for the high-risk. Pleurodesis is a procedure to adhere your lungs to your chest wall. We explain the procedure, the recovery process, and its potential complications

Talc pleurodesis for secondary pneumothorax in elderly

The median age at talc pleurodesis in contacted patients (n = 59) was 29 (17-68) yrs and 45 patients were male. Talc pleurodesis was performed for recurrent pneumothorax in 40 (68%) patients, for persistent air leakage in 17 (29%) patients and in two (3%) patients wishing an immediate intervention for their first episode of primary spontaneous pneumothorax VATS- Talc pleurodesis is an indicated procedure for patients that have malignant pleural effusions and recurrent pneumothorax. In patients diagnosed with malignant pleural mesothelioma, pleural effusions have been reported to be present in up to 90% of the patients.. Video-assisted thoracic surgery, commonly referred to as a VATS procedure, is a minimally invasive surgical technique used to. Pleurodesis decreases the chance of pneumothorax recurrence and should be performed in consultation with the surgeon. This procedure should be performed just after reinflation of the lung if the. VATS talc pleurodesis. with talc pleurodesis had a Dose of asbestos free Retrospective Re-investigated in contralateral PSP treated with talc between 0.5-4 g cohort study 1985. Four had emigrated, hypertonic glucose infusion to (average of 3 g) (level 3b) 26 had died, four did not the pleural space participate, 15 ha

Talc pleurodesis installs talc in the pleural space to intentionally cause inflammation and fibrosis - closing up the space between the lungs and the chest wall. During this procedure, a surgeon will typically spray a mixture of talc and saline through a tube into the chest area that surrounds the lungs From 1978 to 1985 96 patients with their first spontaneous pneumothorax were randomised into three groups, receiving either treatment with simple drainage (34 patients), drainage with tetracycline pleurodesis (33 patients), or drainage with talc pleurodesis (29 patients). There were 58 men and 38 women, aged 18-88 years A retrospective study was performed of the evaluable data in 710 patients with a spontaneous pneumothorax. The male:female ratio was 3.4:1. A thoracoscopy was performed in 622 patients. The two main therapeutic strategies were pleurodesis with talc poudrage (n = 356) and thoracotomy (n = 248). The success rate of talc poudrage was 88 percent.

Talc pleurodesis safe for primary spontaneous pneumothorax

Talc pleurodesis is one of the chemical methods of pleurodesis which is a procedure performed to prevent recurrence of a pneumothorax or recurrent pleural effusion in benign or malignant conditions. It involves achieving an area of adhesion between the parietal and visceral layers of the pleura. Radiographic features CT. After talc pleurodesis, the pleural space can reveal variable degrees of. Thoracoscopic talc pleurodesis, talc slurry pleurodesis. Short name: Talc pleurodesis. Reason for procedure: Pleurodesis is performed in the presence of a pleural effusion. An effusion is a collection of fluid around the lung, in the space between the ribs and the lung. It puts pressure on the lung, collapsing it and causing breathlessness Pleurodesis is a procedure performed to obliterate the pleural space to prevent recurrent pleural effusions, pneumothorax, or to treat a persistent pneumothorax. Pleurodesis is commonly accomplished by draining the pleural fluid or intrapleural air followed by either a mechanical procedure or instilling a chemical irritant into the pleural. Talc pleurodesis was attempted, a chest tube was inserted, and the right lung reexpanded. Six days after lung reexpansion, the chest tube was removed. The patient remained well without any recurrence of pneumothorax after talc pleurodesis. On October 20, 1990, the patient was readmitted in a toxic septicemic state with status epilepticus..

Chest X-ray performed 24 hours after chemical pleurodesis

Persistent pneumothorax: A pneumothorax is a collapsed lung. It can be treated with a chest tube. It can be treated with a chest tube. If the pneumothorax persists (a persistent air leak), or goes away and then recurs, further treatment (such as pleurodesis) to resolve the pneumothorax or prevent a recurrence is needed Case report: Blebectomy with talc pleurodesis after spontaneous pneumothorax. During my various travels and interviews, I have had the opportunity to meet and talk with thoracic patients from around the world. During a recent trip, I encountered a very nice young woman (in her early 20's**). This is her story below

Chemical pleurodesis for spontaneous pneumothorax

Introduction: Primary spontaneous pneumothorax (PSP) is a condition with high morbidity and an estimated recurrence rate of 23 to 50%, over a one to five-year period. Although there are several options in the management of PSP, talc pleurodesis via thoracoscopy has been shown to be safe, cost-effective and superior to conservative treatment The combination of talc pleurodesis and bronchial occlusion with EWS, when a single, initial interventional treatment fails, can be considered in cases of intractable, inoperable secondary pneumothorax Talc slurry for pleurodesis Note: Talc is an unlicensed medicine and should ONLY be used on the advice of a respiratory specialist. Background Pleurodesis is a procedure used to treat recurrent pleural effusions or pneumothorax. Talc is the chemical sclerosant of choice for pleurodesis. 1 Pre-medicatio

Pleurodesis For Spontaneous Pneumothorax - CHES

Talc pleurodesis - UpToDat

Pneumothorax, or a collapsed lung, is the result of a change in pressure around the pleural cavity which prevents the diaphragm from opening the lung, If the patient is too unwell to undergo surgery, a talc pleurodesis is recommended as pneumothorax treatment Guideline for the procedure of Pleurodesis with Talc Slurry WAHT-RES-003 Page 7 of 9 Version 6 APPENDIX 1: GUIDELINE FOR THE PROCEDURE OF PLEURODESIS WITH TALC SLURRY: DOCTOR'S SUMMARY PRE-TALC INSTILLATION Arrange supply of talc from pharmacy. Drain effusion to dryness (confirm by X-Ray). Inform patient & gain consent

Complications of thoracoscopic talc insufflation for the

Chemical pleurodesis is the instillation of either sterile talc or erythromycin to produce irritation or inflammation of the pleura. With bedside pleurodesis or tube thoracostomy pleurodesis, sterile talc is mixed with lidocaine and sterile water to create a talc slurry Pleurodesis may prevent two conditions: pleural effusion and pneumothorax. Pleural effusion is sometimes referred to as water in the lungs. It's a buildup of fluid in the pleura, the thin membranes that line the lungs and chest cavity to help with breathing. Pneumothorax is a collapsed lung

In 12 case series (14 to 356 patients) totaling 659 patients treated with talc poudrage for pneumothorax, 1 (0.15%) patient with respiratory failure was reported . However, the true number of patients receiving talc pleurodesis and the associated cases of acute respiratory failure are unknown Background: We herein report the usefulness of two types of talc pleurodesis for secondary pneumothorax of elderly patients with persistent air leak who have severe pulmonary emphysema. Methods: We assessed 17 elderly patients with persistent air leak who received talc pleurodesis for secondary pneumothorax from April 2013 to March 2017. Thoracoscopic talc poudrage (TTP) (n=11) was performed. One study of 418 patients diagnosed with spontaneous pneumothorax demonstrated no incidence of ARDS or pneumonitis after low doses of talc (2 g), where medium-sized talc particles (31.5 µm) were utilized . Despite this, due to the concern for ARDS, talc pleurodesis is not a recommended form of chemical pleurodesis

A pooled estimate of the effect of chemical pleurodesis alone (talc, tetracycline, minocycline and autologous blood patch) on pneumothorax recurrence found a recurrence rate that had ranges of 2.5-10% (talc poudrage via medical thoracoscopy or VATS), 3-30% (tetracycline through chest drain) and 15.6-18.2% (blood patch through chest drain) The efficacy of chemical pleurodesis in pneumothorax patients is well established in clinical practice [3, 4], and talc is the substance most commonly used worldwide despite the occurrence of severe side effects including acute respiratory distress syndrome (ARDS) [5-7]. This report details the occurrence of hemoptysis in combination with.

Talc. Talc pleurodesis is the most well-established, effective and widely performed technique used to manage persistent pneumothorax and pleural effusion in benign or malignant disease. Pleurodesis with talc has a success rate ranging from 80 % to over 90 % [2, 3] Talc insufflation of the pleural cavity either by VATS or by medical thoracoscopy is safe and effective for primary spontaneous pneumothorax (30, 31), although it has been reported that talc may cause granuloma formation and decrease pulmonary function after long-term follow-up . In this study, minocycline was selected for chemical pleurodesis. Collapse after pleurodesis (talc) procedure? Hey guy, I've had for lung collapses, and have had the pleurodesis procedure done on both lungs. All 4 times my lungs have collapsed he symptoms were: my back and neck were very sore, my chest hurt, I couldn't complete a full sentence, when I walked my body deteriorated in minutes, and when I sat. Talc pleurodesis is used to avoid recurrences in malignant pleural effusions or pneumothorax. The lack of lung sliding detected by chest ultrasonography (CUS) after talc application is indicative of the effectiveness of pleurodesis. The objective of our study was to explore, in an animal model, the capacity of CUS to predict the quality of a symphysis induced by talc poudrage (TP) and talc.

Pleurodesis - StatPearls - NCBI Bookshel

Video: Effectiveness of chemical pleurodesis in spontaneous

Recurrent pneumothorax is a rather uncommon finding in patients with neuromuscular diseases. For cases that happen to patients with neuromuscular diseases while on non-invasive positive pressure ventilation, pneumothorax could be fatal. Medical staff must be vigilant for this complication. Recurrent pneumothorax can be treated with either medical or surgical pleurodesis, depending on the. Pleurodesis is a medical procedure in which the pleural space is artificially obliterated. It involves the adhesion of the two pleurae. Pleurodesis is performed to prevent recurrence of pneumothorax or recurrent pleural effusion. It can be done chemically or surgically TS was probably used on the grounds that age was reported as one of the independent risk factors of recurrence in patients with PSP15 and major guidelines recommended talc pleurodesis for the management of spontaneous pneumothorax.16 17 Patients in the DS group, who were younger and more frequently received surgical interventions prior to. Pneumothorax and hydro-pneumothorax are the most common thoracic injuries and poses a risk of serious morbidity.To prevent the lung from collapsing in such condition, pleurodesis procedure is performed either with surgical pleurodesis,or chemical pleurodesis which adheres outside the lung to the inside chest cavity

Talc Pleurodesis Leanne Connelly Review Date February 2013 Clamp the intercostal chest drain and disconnect the tubing. Instill the local anaesthetic immediately prior to the talc slurry solution via the intercostal chest drain under aseptic technique. Instil the slurry via the intercostal chest drain under aseptic technique. Chemical (using talc, doxycycline, bleomycin or other agents). While chemical pleurodesis through a chest tube can be successful, this may result in incomplete pleurodesis due to the uneven distribution of the chemical. Surgery - Surgical treatment, using video-assisted thoracoscopy (VATS), is the preferred approach

collapsed lung tension pneumothorax punctured lung. In medicine, talc is used as a pleurodesis agent to prevent recurrent pleural effusion or pneumothorax. Soapstone Mohs scale of mineral hardness Magnesium Baby powder Talc carbonate. Cystic fibrosis. 50% (1/1) CF Cystic fibrosis of the pancreas disease Previous pneumothorax with or without pleurodesis is not a contraindication to subsequent lung transplantation. Chemical [ edit ] Chemicals such as bleomycin , tetracycline (e.g., minocycline ), [2] povidone-iodine , or a slurry of talc can be introduced into the pleural space through a chest drain The success rate of pleurodesis was 93.3% in the talc group and 96% in the Viscum group (p = 0.225).Conclusion Viscum pleurodesis showed comparable treatment results with talc pleurodesis while. Talc pleurodesis is considered to be a safe and effective treatment modality in the management of (recurrent) spontaneous pneumothorax. In literature, increased pleural FDG-uptake on PET scanning is described for up to five years after the initial procedure [ 1 - 3 ]

Pleurodesis: Complications, Side Effects, and Recover

Median duration of follow-up after talc pleurodesis was 118 months. Long-term success was observed in 53 (95%) out of 56 patients. Recurrent pneumothorax was observed in three (5%) out of 56 patients. Patients with successful talc pleurodesis had a median forced vital capacity (FVC) of 102% and median total lung capacity of 99% at follow-up PDF | The purpose of this article is to report a case of hemoptysis occurring in combination with secondary spontaneous pneumothorax following chemical... | Find, read and cite all the research. Jin-Shing Chen and colleagues randomly assigned patients with first episodes of primary spontaneous pneumothorax to simple aspiration via a pigtail catheter (n=108) or catheter drainage followed by minocycline pleurodesis (n=106); interventions were administered immediately after radiographic confirmation of complete lung expansion and cessation of air leak Two studies looked at talc pleurodesis via tube thoracostomy (TT) alone for patients with secondary spontaneous pneumothorax (SSP). Talc pleurodesis was associated with an immediate success rate of 78.1 and 78.6%, with a short-term recurrence rate of 21.9 and 21.4% Talc pleurodesis, January 2020 Patient information - Talc pleurodesis If you are unable to have a talc pleurodesis or do not wish to have one, then we can arrange repeat fluid removal when necessary. What are the risks of a talc pleurodesis? Inserting talc into the pleural space causes inflammation and therefore pain is a frequent side effect

Intractable pneumothorax managed by talc pleurodesis and bronchial occlusion with spigots Intractable pneumothorax managed by talc pleurodesis and bronchial occlusion with spigots Ishida, Atsuko; Kida, Hirotaka; Muraoka, Hiromi; Nishine, Hiroki; Mineshita, Masamichi; Miyazawa, Teruomi 2015-03-01 00:00:00 Three cases of inoperable secondary spontaneous pneumothorax were diagnosed in patients. Hunt I, Barber B, Southon R, et al. Is talc pleurodesis safe for young patients following primary spontaneous pneumothorax? Interact Cardiovasc Thorac Surg 2007;6:117-20. Györik S, Erni S, Studler U, et al. Long-term follow-up of thoracoscopic talc pleurodesis for primary spontaneous pneumothorax. Eur Respir J 2007;29:757-60

Dive into the research topics of 'Talc pleurodesis'. Together they form a unique fingerprint. Sort by Weight Alphabetically Medicine & Life Sciences. Talc 100%. Pleurodesis 98%. Pleura 36%. Thoracoscopy 19%. Pleural Effusion 16%. Malignant Pleural Pneumothorax 8%. Powered by Pure,. Chest ultrasonography to assess the kinetics and efficacy of talc pleurodesis in a model of pneumothorax: an experimental animal study Rachid Tazi-Mezalek 1,2, Diane Frankel3,4, Marc Fortin5, Elise Kaspi3,4, Julien Guinde1,4, Alexandra Assolen4, Sophie Laroumagne1,2, Andree Robaglia3,4, Herve Dutau1, Patrice Roll3,4 and Philippe Astoul1,2,6 Affiliations: 1AP-HM, Hôpital Nord, Dept of Thoracic. Talc pleurodesis Experience with 360 patients Talc was used intrapleurally for the creation of pleural adhesions in 360 patients. The indications for use were malignant pleural effusion in 169 patients, benign effusions in 41, recurrent pneumothorax in 122, empyema in 19, and chylothorax in 9. Of 336 patients available for foUow-up, exceUent.

pneumothorax. Methods The study included 54 patients with malignant pleu-ral effusion and recurrent spontaneous pneumothorax, who un-derwent talc pleurodesis using the talc slurry method of pleural talc obliteration. ResultsPleurodesis was successful in 52 (96%) patients. The ave BACKGROUND: Complicated (recurring or persistent) spontaneous pneumothorax requires intervention either by surgical or nonsurgical pleurodesis or other interventions. As for high-risk patients, aggressive interventions may be associated with morbidity, the safety and effectiveness of less aggressive alternative interventions like thoracoscopic. Povidone-iodine pleurodesis can be considered as a good alternative to Talc pleurodesis for recurrent malignant pleural effusion. The drug is available, cost effective, safe and can be administered through an intercostal drain and repeated if necessary

Effectiveness of Thoracoscopic Talc Pleurodesis in the

  1. The main solution to fixing a repeated lung collapse is to physically scrape and scar the surface of the lung with surgical tools (a mechanical pleurodesis), or to chemically burn the lung using antibiotics or Talc (a chemical pleurodesis), or to tear out the lining of the lung (a pleurectomy)
  2. the recurrence of pneumothorax proposed by the Novatech is, however, a new one. Steritalc has been available on the European market as a medical device for more than 20 years. As outlined in the pulmonary consult, talc has been used in the management of pneumothorax since the 1940's. The pleurodesis options to reduce recurrence o
  3. Tetracycline and talc are well-studied effective agents for medical pleurodesis; talc was 5% more effective in one randomized study. Success rates for chemical sclerosing agents are up to 91% versus 95-100% in surgical techniques
  4. istration of various chemical agents (e.g. talk, tetracycline, iodopovidone, etc.). The two major clinical conditions treated with chemical pleurodesis are recurrent pleural effusion (PE) and recurrent spontaneous pneumothorax


Pneumothorax is a potentially life-threatening complication of chronic obstructive pulmonary disease (COPD) that leads to cardiopulmonary compromise. According to the British Thoracic Society (BTS) guidelines, medical pleurodesis is recommended for inoperable patients suffering from COPD-related pneumothorax. Several sclerosing agents are currently in use, but none have been proven to be the. Talc pleurodesis in young patients with a primary pneumothorax appears to have minimal long-term adverse effects. References Cardillo G, Carleo F, Giunti R, Carbone L, Mariotta S, Salvadori L, Petrella L, Martelli M. Videothoracoscopic talc poudrage in primary spontaneous pneumothorax: a single-institution experience in 861 cases Chemical pleurodesis has also been tried with talc, and minocycline and have shown recurrence rates of 1.73-5% (12, 13) and 2.9% , respectively. Other reported methods include electrocoagulation of the pleura and ablation with Nd:YAG laser. At our institution, VATS is conducted for pneumothorax with a 2-mm thoracoscope and instruments from 2003 An earlier smaller randomised study including participants with primary and secondary pneumothorax compared simple drainage with tetracycline or talc pleurodesis and found that the rate of recurrence over a mean follow-up period of 4.6 years was only 8% in the talc pleurodesis group but 36% in the simple drainage group.24 British Thoracic.

  1. talc pleurodesis for treatment of pneumothorax had been shown to have a successful rate of 91% in a series of studies from 1947 to 1994.8 However, high potency means it would induce a stronger inflammatory response in the pleura and causes more adverse effects. Fever is common after talc pleurodesis as the inflammatory cytokines can enter the.
  2. Talc pleurodesis is 90-95% effective at prevention of recurrent primary spontaneous pneumothorax. However, there have been reports of ARDS occurring after talc pleurodesis, mostly in patients with malignant pleural effusions, raising concerns over its use
  3. We did a prospective cohort study to measure the side-effects of thoracoscopy and pleurodesis by poudrage with large-particle talc for treatment of recurrent malignant pleural effusions. 14 centres (all departments of pulmonary diseases) participated in the study, 13 in Europe and one in South Africa, between Oct 1, 2002, and Oct 31, 2005
  4. Pleurodesis Pleurodesis is the artificial obliteration of the pleural space by adhesion of the two pleurae The role of pleurodesis Chemical pleurodesis with talc slurry to obliterate the pleural space is recommended when a patient is not suitable for VATS pleurodesis (video-assisted thorascopic surgery) It should only be performed under the supervision of a respiratory team Pleurodesis [

Long-term follow-up of thoracoscopic talc pleurodesis for

  1. imally invasive procedure in which a thin plastic tube is inserted into the pleural space — the area between the chest wall and lungs — and may be attached to a suction device to remove excess fluid or air. A chest tube may also be used to deliver medications into the pleural space
  2. ocycline.[3,5-12] The decision on use of each agent will depend on the indication, availability of the products, and healthcare professional knowledge and preference
  3. different medicines that can be used in pleurodesis, and the doctors and nurses looking after you will talk to you about the specific one they use. A commonly used pleurodesis drug is sterile medical talc. The drug is usually injected in liquid form, but if you are having a thoracoscopy procedure, the pleurodesis drug will be applied as a powder
  4. have described after talc pleurodesis may be due to the pleurodesis itself, regardless of method, although there is a lack of data to answer this question. As to the oncologic risk, the use of asbestos-free talc seems to remove the risk of mesothelioma or lung cancer
Pleurodesis: Complications, Side Effects, and RecoveryPleural Talc - LifeHealthcare

Likewise, people ask, what is talc pleurodesis? Pleurodesis is a procedure performed to obliterate the pleural space to prevent recurrent pleural effusion or pneumothorax or to a treat persistent pneumothorax.Talc pleurodesis is a specific form of chemical pleurodesis.. Also Know, how is a pleurodesis performed? A pleurodesis procedure is usually performed through a chest tube placed at the. A Japanese male with cancer of renal pelvis was found with the left pneumothorax and multiple lung metastases. A computed-tomography scan revealed severe emphysema throughout the lungs. Talc pleurodesis was employed to arrest air leakage. The patient developed hemoptysis 45 minutes after talc injection into the thorax We prospectively conducted adjuvant pleurodesis with a 20% dextrose solution or talc -20% dextrose mixed solution during thoracoscopic procedures in patients with primary spontaneous pneumothorax. The effects were evaluated by comparing outcomes of the patients who underwent thoracoscopic procedures alone with those who underwent additional. Results. Out of 43 included patients with pneumothorax, five patients were excluded and remaining 38 patients were subjected to pleurodesis. Demographic and basic clinical profile of study population are shown in Table 1.. Cause of pneumothorax was Primary spontaneous pneumothorax in five, COPD in 12, Tuberculosis (healed and active cases) in 14, Bronchiectasis (Non tubercular) in three. The complications of tetracycline pleurodesis have been described,2 and talc pleurodesis may be non-licensed and cause adult respiratory distress if talc with small particles is used.3 Therefore we highlight the use of blood pleurodesis to successfully resolve an iatrogenic pneumothorax, which resulted in immediate resolution and did not result.