Systemic lupus erythematosus. Dr Daniel J Bell and Dr Yuranga Weerakkody et al. Systemic lupus erythematosus ( SLE) is a complex autoimmune disease with multisystem involvement. Although abnormalities in almost every aspect of the immune system have been found, the key defect is thought to result from a loss of self-tolerance to autoantigens Pericarditis constitutes the most frequent cardiac and/or pericardial manifestation in patients with systemic lupus erythematosus and can also be found in patients with virtually all forms of primary vasculitis and, less frequently, in patients with other systemic diseases (rheumatoid arthritis) The aim of this study was to describe the clinical, echocardiographic and laboratory characteristics of large pericardial effusions and cardiac tamponade secondary to systemic lupus erythematosus (SLE). An ongoing prospective study was conducted at Tygerberg Academic Hospital, South Africa between 1 Gastrointestinal Radiology / Radiologie gastro-intestinale. Systemic lupus erythematosus is an immune-mediated syndrome in which the immune response is to non-organ-specific antigens, and virtually every organ in the abdominal cavity may become involved. constrictive pericarditis, and peritoneal inflammation secondary to vasculitis. Pericarditis is a common cardiac manifestation in systemic lupus erythematosus (SLE). Serositis is recognized in the ACR, SLICC, and EULAR/ACR classification criteria. We reviewed the prior research regarding the epidemiology, risk factors, presentation, and treatment of pericarditis in SLE
Aim of the study: To establish the presence of pericarditis and exudative pleuritis in patients with systemic lupus erythematosus (SLE) prior to and after glicocorticoid and cytotoxic therapy. Patients and methods: In 43 patients, 39 women and 4 men, with SLE (disease was diagnosed according to revised American College of Rheumatology ACR criterias, 1997), aged between 20 and 61 and averaged. Lupus can also cause inflammation in different parts of the heart: Endocarditis is inflammation in the heart walls and valves. It can cause clumps of material to build up on the heart valves, which may break off and form blood clots. Myocarditis is inflammation in the heart muscle In some cases, lupus can trigger the inflammation of the thin sac surrounding the heart, known as the pericardium. When this happens, the condition is called pericarditis or lupus pericarditis. Lupus patients tend to develop pericarditis more than any other disease related to the heart Pericarditis is a common heart complication as a result of lupus. The pericardium is a protective cushion that surrounds the heart and cushions the chest. Lupus can cause the pericardium to become..
Pericarditis from flare. Hello, I was just wondering if anyone has had pericarditis as a result of a flare? And how common is it? I had a severe bout when my lupus flare progressed initially (12 years ago) and had steroids to counteract it. I have noticed recently (last 12/18m) that whenever I now have a flare it just seems to go straight to my. Ontology: Lupus Erythematosus, Systemic (C0024141) Definition (NCI_NCI-GLOSS) A chronic, inflammatory, connective tissue disease that can affect many organs including the joints, skin, heart, lungs, kidneys, and nervous system. It is marked by many different symptoms; however, not everyone with SLE has all of the symptoms . She was diagnosed with systemic lupus erythematosus with early constrictive pericarditis, cutaneous lupus and serositis in the form of pericardial and pleural effusion. There was no renal, neurological and joint involvement. She was treated with steroid pulse and other ancillary drugs. Pericarditis has an incidence of 20-30% and is the most common presentation of heart involvement clinically, although examination rubs are less common. It is usually associated with small.
Lupus pericarditis is the most common cardiac manifestation of SLE and is one of the inclusion criteria in the ACR classification of SLE. 34 Combined autopsy series revealed that pericardial involvement occurred in more than 60% of SLE patients, although only 25% of these cases presented clinically with pericarditis. 35 Pathologically, it most. Localized pericardial inflammation in systemic lupus erythematosus. Ben-Horin S(1), Portnoy O, Pauzner R, Livneh A. Author information: (1)Medicine F, Sheba Medical Center, Sackler School of Medicine, Tel-Aviv University, Tel-Hashomer, Israel. Regional or localized pericarditis has been infrequently reported Some people with lupus develop pericarditis (fluid around the heart) during a flare. The symptoms are sharp chest pain with breathing and a shortness of breath. The treatment is usually non-steroidal medications, such as ibuprofen and naproxen, or short courses of steroids, like prednisone
Many infectious and metabolic diseases, tumors, radiation, drug reactions, and collagen disorders, such as systemic lupus erythematosus and scleroderma, typically cause small pericardial effusions. Uremic pericarditis occurs in about 50% of patients with chronic renal failure and is an indication for dialysis Pericarditis is essentially a fibrotic inflammatory reaction of the pericardium brought on by a large number of conditions, including radiation therapy, post cardiac surgery or post myocardial infarction (Dressler's syndrome), or by drugs, uraemia, infection (e.g. viral, bacterial tuberculosis), and hypothyroidism [16, 20] Pericardial effusion, a common clinical finding, is provoked by a variety of infectious and noninfectious processes. The primary aim in treating patients with symptomatic pericardial effusion is relief of the symptoms, although secondary aims should include determination of the cause of the effusion and prevention of recurrence .Pericardial effusion develops as transudate (hydropericardium.
In lupus myocarditis there was greater involvement of the ejection fraction of the left ventricle, pericardial (pericardial effusion 60% and 73% of patients with pericarditis) and valvulitis (86%) involvement, characteristics that were not identified in viral myocarditis .54 +/- 5.74 years, heart/lung radiology and heart echosonography were performed in order to discover possible serositis (pericarditis and.
Clinical investigation for a pericarditis cause is indicated in the presence of systemic symptoms high fever, hypotension, increased jugular vein pressure, subacute onset, and immunocompromised status .There are certain clues assisting in the diagnosis of pericarditis secondary to a rheumatologic cause (Table 1).This has prognostic significance as pericarditis in the context of rheumatologic. Systemic lupus erythematosus (lupus) is a chronic autoimmune disease that causes the body's immune system to malfunction and attack its own healthy cells and tissues, causing a range of diverse symptoms including rashes, fatigue, pain and fever. It affects each person differently, and often develops slowly, over time. Lupus can affect various parts of the body, including joints, tendons. Am Fam Physician. 2002 Nov 1;66 (9):1695-1702. Pericarditis, or inflammation of the pericardium, is most often caused by viral infection. It can also develop as a result of bacterial or other. • A patient treated for two months with the antihypertensive agent minoxidil developed pleural and pericardial effusions in association with a positive antinuclear antibody titer. No evidence of central nervous system or renal involvement was present, and results of specific tests for idiopathic.. Constrictive pericarditis in systemic lupus erythematosus. Demonstration of immunoglobulins in the pericardium. Arthritis Rheum. 1978; 21:972-974. doi: 10.1002/art.1780210815 Crossref Medline Google Scholar; 3. Nishimura RA. Constrictive pericarditis in the modern era: a diagnostic dilemma. Heart
OBJECTIVES To determine the frequency and type of cardiac manifestations in children with systemic lupus erythematosus (SLE) and investigate whether cardiac involvement of SLE in children was associated with any autoantibody pattern. METHODS Retrospective analysis of the medical records of all children with SLE (31 patients) seen between January 1984 and January 1994 by the paediatric. Weissman BN, Rappoport AS, Sosman JL, Schur PH. Radiographic findings in the hands in patients with systemic lupus erythematosus. Radiology 1978; 126:313. Ruano CA, Malheiro R, Oliveira JF, et al. Ultrasound detects subclinical joint inflammation in the hands and wrists of patients with systemic lupus erythematosus without musculoskeletal symptoms Concomitance of acute pericarditis and pulmonary embolism is extremely rare, with only a few case reports published so far. Herein we present a case of a 50-year-old man that presented to the Emergency Department, complaining of fever up to 38.5 o C, pleuritic chest pain, nausea, arthralgias, and general symptoms during the previous two weeks
Roentgenographic Manifestations of Joint Disease in Systemic Lupus Erythematosus Roentgenographic Manifestations of Joint Disease in Systemic Lupus Erythematosus Noonan, Charles D.; Odone, Donald T.; Engleman, Ephraim P.; Splitter, Stanford D. 1963-05-01 00:00:00 YSTE MI C LUPUS TABLE I: DIAGNOSTIC CRITERIA FOR Lupus ERYTHEMATOSUS* SYSTEMIC Value 3 Value 2 Value 1 Value 1/2 Positive L.E. We report a particular case of PRES involving the brainstem and capsular-thalamic regions in a patient with systemic lupus erythematosus (SLE). A 25-year-old female, with a 5-year history of SLE with several manifestations (HT, seizures, lupus nephritis, pericarditis), was admitted for sudden onset of impaired consciousness and double vision Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that can affect all organ systems. Involvement of the cardiovascular system is often seen in SLE, most commonly manifested as pericarditis . Myocarditis is uncommon. The gold standard for diagnosis of myocarditis is endomyocardial biopsy (EMB) . Therapy with amphotericin B and properly timed surgical intervention led to a clinical and microbiological cure. This article emphasizes the importance of..
Lupus is a disease that causes episodes of inflammation and damage to many parts of the body, including the skin and organs. It is caused by both genes and environmental factors. Symptoms include a rash, fever, joint inflammation and pain, and sensitivity to the sun. Lupus can range from a mild disease to a life-threatening disease The term undifferentiated connective tissue disease (UCTD) is used to describe a condition in people who have symptoms and lab test results that indicate a systemic autoimmune disorder or connective tissue disease, but which do not meet enough such characteristics to indicate a diagnosis for a well-defined connective tissue disease such as.
Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease that predominantly affects women of childbearing age. The exact cause is still unknown, but hormonal and immunological features as well as genetic predisposition are considered likely etiological factors. The presentation of the disease is variable but usually characterized. . The pericardium holds the heart in place and helps it work properly. There is a small amount of fluid between the inner and outer layers of the pericardium. This fluid keeps the layers from rubbing as the heart moves to pump blood
Clinically evident pericarditis has been reported in 25% of patients with SLE and usually occurs in lupus flare-ups, but it may be the presenting manifestation. Autopsy series reveal pericardial. SCleroderma Radiology 120:269-275, August 1976 Diagnostic Radiology â ¢ scleroderma and systemic lupus erythematosus (SLE) are usually distinctive and diagnostic. Occasionally, typical features of one disease may be seen in the other (2,5,8, 15), or both diseases may coexist in a single patient (1,3, 5, 19) Chronic pericarditis is inflammation of the pericardium (the flexible two-layered sac that envelops the heart) that begins gradually, is long-lasting, and results in fluid accumulation in the pericardial space or thickening of the pericardium. Symptoms may include shortness of breath, coughing, and fatigue Lupus can contribute to pericarditis - inflammation of the pericardium, a part of the heart. Article by Bel Marra Health. 4. Types Of Heart Disease Heart Disease Symptoms Natural Blood Pressure Lower Blood Pressure Trauma Cardiac Arrhythmia Cardiac Nursing Heart Conditions Science
Lupus is an autoimmune disease that causes symptoms and signs like a butterfly rash, arthritis, hair loss, and ulcers of the nose and mouth. Read about lupus treatment, diagnosis, prognosis, causes, pregnancy flares, and diet. Also, see pictures Viral infections are likely the most common cause of acute pericarditis, but the virus may never be found. Pericarditis often occurs after a respiratory infection. Bacterial, fungal, and other infections also can cause pericarditis. Less often, pericarditis is caused by: Autoimmune disorders, such as lupus, scleroderma, and rheumatoid arthriti
Systemic lupus erythematosus (SLE) is an autoimmune disease. In this disease, the immune system of the body mistakenly attacks healthy tissue. It can affect the skin, joints, kidneys, brain, and other organs. Systemic lupus erythematosus is a chronic inflammatory autoimmune disorder which may affect many organ systems including the skin, joints. Although this patient's symptoms arose because of untreated pulmonary tuberculosis, constrictive calcific pericarditis can result from many processes, including chest trauma, the aftereffects of radiation, connective tissue diseases (e.g., lupus, rheumatoid arthritis) and infections (e.g., tuberculosis, histoplasmosis)
Systemic lupus erythematosus (SLE or lupus) is a disease that causes your body's immune system to attack its own cells and tissues. It causes episodes of inflammation to various parts of the body. It can affect your joints, tendons, and skin. It can affect blood vessels. And it can affect organs such as the kidneys, heart, lungs, and brain Diffuse alveolar hemorrhage (DAH) due to capillaritis is rare (occurring in 1-2% of cases) and associated with high mortality. [52, 53] It is characterized by fever, cough, dyspnea, hypoxia, and hemoptysis.The presentation is similar to that of acute lupus pneumonitis; however, in DAH, the diffusion capacity of the lung for carbon monoxide (DLCO) is usually high, and lupus nephritis is present
Lupus is diagnosed when four clinical and laboratory features are present. American College of Rheumatology (ACR) Criteria for the Classification of SLE According to the ACR criteria, a person is defined as having SLE if any four or more of the 11 following criteria are present, serially or simultaneously, during any interval of observation Systemic lupus erythematosus (SLE), also known as lupus, is an autoimmune disease where the immune system mistakenly attacks healthy tissues throughout the body. With lupus, a person's overactive immune causes inflammation that damages connective tissues, including cartilage and the lining of the blood vessels The pericardium is a fluid-filled sac that wraps around the heart and expands and contracts as it beats. Think of the pericardium as a water balloon that protects the heart by cushioning it from other organs in the chest, such as the lungs, the diaphragm (breathing muscle), and the trachea (windpipe) Connective tissue disorders including systemic lupus erythematosus, rheumatoid arthritis, systemic sclerosis or scleroderma (and more) are important causes of pericardial diseases. Acute pericarditis following an ST-elevation myocardial infarction, which is also called Dressler's syndrome, should be anticipated and managed accordingly Suggested therapies for cutaneous lupus erythematosus (CLE). All patients should be counseled about daily sun protection, as both UVA and UVB can trigger flares of CLE and may even lead to exacerbations of systemic symptoms. Topical therapy is indicated in local disease and as an adjunct to systemic therapy in severe and widespread CLE
Pericarditis may be caused by viral, bacterial, or fungal infection. Classic bread-and-butter appearance of fibrinous pericarditis had been described in rheumatic disease and other immunologic diseases such as systemic lupus erythematosus, post-myocardial infarct, uremia, tuberculosis, radiation effects, bacterial, and viral etiology Pericarditis is the inflammation of the pericardial sac that surrounds the heart. The causes of pericarditis include injury from heart attack, heart surgery, trauma, viral or fungal infection, HIV, tumors, mixed connective tissue disease, metabolic disease, medication reactions, or unknown reasons. Treatment for pericarditis is generally. In patients with lupus, there is a pancarditis, which has been described. 1 Myocarditis is usually subclinical and fairly infrequent in terms of its clinical manifestations. It is seen at autopsy, however, in as many as 40% of cases. Overt heart failure from lupus myocarditis is rather rare. Pericarditis is the most common cardiac manifestation GoykhmanP, et al Subendocardial Ischemia and Myocarditis in Systemic Lupus Erythematosus Detected by Cardiac Magnetic Resonance Imaging The Journal of Rheumatology February 2012, 39 (2) 448-450; Kreps , A et al Cardiac Manifestations in Systemic Lupus Erythematosus: A Case Report and Review of the Literature Am J Med Case Rep. 2018; 6(9): 180. Background In systemic lupus erythematosus (SLE), cardiac manifestations, e.g. coronary artery disease (CAD) and myocarditis are leading causes of morbidity and mortality. The prevalence of subclinical heart disease in SLE is unknown. We studied whether a comprehensive cardiovascular magnetic resonance (CMR) protocol may be useful for early diagnosis of heart disease in SLE patients without.
Drug-induced systemic lupus erythematosus may also produce pericarditis; the culprit agents include hydralazine, procainamide, and isoniazid. Most of these causes can induce both dry pericarditis and pericardial effusive disease, or wet pericarditis Acute pericarditis has a number of potential etiologies including infection, acute myocardial infarction, medication use, trauma to the thoracic cavity, and systemic diseases, such as rheumatoid. Radiology 2013; 267:340-356. Imazio M, Spodick DH, Brucato A, Trinchero R, Adler Y. Controversial issues in the management of pericardial diseases. Circulation 2010; 121:916-928. Imazio M, Brucato A, Mayosi BM, et al. Medical therapy of pericardial diseases: part I: idiopathic and infectious pericarditis 65 year old female with longstanding history of SLE, Lupus Sjogren's and Raynaud's. JACCOUD'S ARTHROPATHY 65 year old female with longstanding history of SLE, Lupus Sjogren's and Raynaud's Xray shows non erosive arthropathy with ulnar deviation of 2nd through 5th MCP joints SLE Heart. Pancarditis pericardium, pericarditis 25% most commo Lupus is a disease that causes episodes of inflammation and damage to many parts of the body, including the skin and organs. It is caused by both genes and environmental factors. Symptoms include a rash, fever, joint inflammation and pain, and sensitivity to the sun. Lupus can range from a mild disease to a life-threatening disease
Patients with systemic lupus erythematosus (SLE) presenting with chest pain pose a unique diagnostic challenge, with causes ranging from cardiopulmonary disease to esophageal disorders and musculoskeletal chest wall pain. The most common biomarkers for myocardial injury are cardiac troponin T and I (cTnT and cTnI) due to their high sensitivity for the early detection of myocardial infarction -pericarditis is most common cardiac problem; occurs in 30-40% of patients-accompanied by pleural effusions-congenital heart defects can occur in infants of mothers with SLE-secondary heart disease can occur-hypertension is associated with lupus nephritis and long term corticosteroid use-ischemic heart disease can occur in the elderl Pericarditis may result from radiation therapy, myocardial infarction, malignancy, systemic diseases such as systemic lupus erythematosus and hypersensitivity reaction, or infection such as tuberculosis and Coxsackie B. Coxsackie B is a common cause of pericarditis but is usually not associated with calcification and symptomatic constriction The ACR Appropriateness Criteria ® (AC) are evidence-based guidelines to assist referring physicians and other providers in making the most appropriate imaging or treatment decision for a specific clinical condition. Employing these guidelines helps providers enhance quality of care and contribute to the most efficacious use of radiology
Serositis is a type of inflammation that affects the serous tissues that protect your organs and allow them to move smoothly within your body. It can affect all your serous membranes or only. Discoid lupus erythematosus (DLE) develops in up to 25% of patients with SLE, but may also occur in the absence of any other clinical feature of SLE. 3 Patients with only DLE have a 5% to 10% risk of eventually developing SLE, which tends to follow a mild course. 4 DLE lesions usually slowly expand with active inflammation at the periphery, and. Diagnosing Systemic Lupus Erythematosus. Systemic lupus erythematosus, commonly known as lupus, is a chronic autoimmune disease. This means that the immune system, which attacks viruses and bacteria, instead attacks healthy tissue, causing inflammation throughout the body and, sometimes, damaging tissue. Lupus can affect the blood vessels. We are reporting a young woman with systemic lupus erythematosus, who was positive for HKU1 during her pericarditis flare. Diagnostic imaging demonstrated pericardial effusion, edema, and late gadolinium enhancement on cardiac magnetic resonance imaging and echocardiography Acute pericarditis is an inflammation of the pericardium characterized by chest pain, pericardial friction rub, and serial ECG changes. The first and last stages of ECG changes are seen in the images below. For You Systemic lupus erythematosus, scleroderma, sarcoidosis
Lupus is a disease of the immune system. Learn more about the symptoms, complication, causes, types, diagnosis, treatment, lifestyle changes, and outlook for lupus Pericarditis causes a specific sound, called a pericardial rub. The noise occurs when the two layers of the sac surrounding your heart (pericardium) rub against each other. Blood tests are usually done to check for signs of a heart attack, inflammation and infection. Other tests used to diagnose pericarditis include Systemic lupus, rheumatoid arthritis, and other autoimmune diseases have been shown to increase your risk for constrictive pericarditis. Pericarditis is a side effect of some medications Pericardial effusion, and the possible inflammation of the pericardium resulting from it (called pericarditis), can have many possible causes, including: Infection such as viral, bacterial or tuberculous; Inflammatory disorders, such as lupus and rheumatoid arthritis; Cancer that has spread (metastasized) to the pericardiu Pericarditis can cause swelling in your feet, legs and ankles. This swelling may be a symptom of constrictive pericarditis. This is a serious type of pericarditis where the pericardium gets hard and/or thick. When this happens, the heart muscle can't expand, and it keeps your heart from working like it should
A chronic inflammatory disorder of the connective tissues, lupus erythematosus appears in two forms: discoid lupus erythematosus, which affects only the skin, and systemic lupus erythematosus (SLE), which affects multiple organ systems (as well as the skin) and can be fatal. Like rheumatoid arthritis, SLE is characterized by recurring remissions and exacerbations, which are especially common. Rarely, acute pericarditis is the initial presentation of a systemic inflammatory disease (SID), i.e. systemic lupus erythematosus (SLE). It is important to recognize that a positive ANA is a non-specific test. A rheumatology consult should be sought in patients with pericarditis in whom a diagnosis of a SID is suspected Drug-Induced Pericarditis is an uncommon condition that is caused by the usage of certain medications. Any individual taking such medication may be at risk for the condition. It can affect both males and females. There is no predilection to any ethnic group or a particular race; the condition is observed worldwide
The normal pericardial sac contains 10-50 mL of pericardial fluid acting as a lubrificant between the pericardial layers. Surprisingly, little is known about the formation and removal of pericardial fluid, because of the paucity of comprehensive studies, especially in human subjects, and methodological difficulties to distinguish between the dynamics of normal pericardial fluid and those of. Systemic lupus erythematosus (SLE) is a chronic, autoimmune, connective tissue disorder with multi-organ involvement. Reported here is the case of a 33-year-young women with a 12-year history of lupus erythematosus. The article documents the development of lupus: First phase/ preliminary phase (13-21 years of life); Second phase/acute cutaneous lupus erythematosus (22-27 years of life); Third. Systemic lupus erythematosus (lupus) is a disease that causes your body's immune system to attack its own cells and tissues. It causes periods of inflammation to various parts of the body. It can affect your joints, tendons, and skin. It can affect blood vessels. And it can affect organs such as the kidneys, heart, lungs, and brain Systemic lupus erythematosus (SLE) is a chronic, lifelong autoimmune disease. It can be mild to severe, and affects mostly women. SLE may affect various parts of the body, but it most often manifests in the skin, joints, blood, and kidneys Discoid lupus erythematosus (DLE) is the most common form of chronic cutaneous lupus erythematosus. Classic DLE lesions begin as red-purple macules, papules or small plaques and rapidly develop a.
Only a history of pericarditis appeared to be associated with positive thallium-201 results (p less than 0.05). It is concluded that segmental myocardial perfusion abnormalities are common in patients with systemic lupus erythematosus. Whether this reflects large-vessel coronary disease or small-vessel abnormalities remains to be determined Systemic Lupus Erythematosus (SLE or Lupus) is an autoimmune disorder that may affect any area of the body such as the skin, joints, blood cells, kidneys, brain, heart, and lungs. Women are more commonly affected by SLE than men Lupus. Lupus is the short name for the condition called systemic lupus erythematosus (SLE). It can cause various symptoms, the most common being joint pains, skin rashes and tiredness. Problems with kidneys and other organs can occur in severe cases. Treatment includes anti-inflammatory painkillers to ease joint pains For 2 weeks, this 13-year-old girl felt tired and achy. She had persistent fevers (temperature up to 38.8°C [102°F]) and an erythematous facial rash above her eyebrows that extended to her cheeks and nasal bridge and spared the nasolabial folds. She had applied a topical acne medication to the rash but noted no improvement. She also reported decreased oral intake because of discomfort from. Lupus is a long-term condition that can cause inflammation in the skin, organs, and in various other places in the body. More often, it causes inflammation in the lining tissues around the heart, known as pericarditis. It can also cause inflammation in the lining of the lungs, known as pleurisy. Both these conditions cause breathlessness.
Gastrointestinal (GI) manifestations are common in patients with systemic lupus erythematosus (SLE). William Osler, in 1895 , was the first to emphasize that the GI manifestations may overshadow other aspects of the disease and mimic any type of abdominal condition.Anorexia, nausea and vomiting are seen in ∼50% of patients with SLE (see Table 1) [2- 5]; however, they may be due to the. radiology after these findings because of suspected lupus myocarditis, cardiac magnetic resonance imaging (MRI) was performed to diagnose the cause of fever. On the four chamber T2 weighted image, there was myocardial edema in the anterior and anterolateral wall (Figure 1A). After intravenous gadolinium injection, delayed-enhanced image Systemic lupus erythematosus (SMQ) () Definition (MDRCZE) Chronická zánětlivá autoimunitní porucha zasahující mnoho tělesných systémů s různou závažností charakterizovanou různými protilátkami.Protilátky dvouvláknové DNA a polypeptidů Sm Protilátky antifosfolipidů (včetně antikoagulantu lupusu, protilátek antikardiolipinu a protilátek, které vedou k falešně. Lupus can cause disease of the skin, heart, lungs, kidneys, joints, and nervous system as well. The condition is called lupus dermatitis or cutaneous lupus erythematosus when only the skin is involved by rash. Discoid lupus erythematosus is a form of lupus dermatitis that can be isolated to the skin, without internal disease Acute pericarditis is the first attack of pericarditis, generally occurring with an acute onset of symptoms. Treatment of the episode generally lasts for 4-6 weeks, considering the attack dose and drug tapering. If the patient does not reach a remission and the disease lasts several weeks or months without a symptoms-free interval of 4-6 weeks, the term incessant pericarditis is adopted
Table 33.6. Suggested therapies for cutaneous lupus erythematosus (CLE). All patients should be counseled about daily sun protection, as both UVA and UVB can trigger flares of CLE and may even lead to exacerbations of systemic symptoms. Topical therapy is indicated in local disease and as an adjunct to systemic therapy in severe and widespread CLE Lupus at a Glance. A group of heterogeneous illnesses that have in common the development of immunity to self-nucleic acids and their associated proteins, with skin-only disease at one end of the spectrum and severe visceral involvement at the other. Skin lesions may be specific to lupus or nonspecific and are seen in other conditions as well WebMD discusses the causes, symptoms, and treatment of pericardial effusion -- an abnormal amount of fluid between the heart and the sac surrounding the heart Pericarditis is an inflammation or infection of the covering of the heart. Pericarditis is most often caused by an infection. Chest pain is the most common symptom of pericarditis. A child may be irritable, feed or eat poorly, and be tired. Treatment of pericarditis includes medicines for inflammation and pain